Models for 10,000 Human Diseases

Cell of the Month: Mast Cells

Mast cells are tissue-resident immune cells derived from the myeloid lineage, and along with basophils, eosinophils and neutrophils, they belong to the granulocyte family of white blood cells.  First discovered and named almost 200 years ago by German pathologist Friedrich Daniel von Recklinghausen and German physician and scientist Paul Ehrlich, mast cells have diverse functions in innate and adaptive immunity, including a major role in allergy and anaphylaxis, as well as inflammation, immune tolerance, tissue repair and angiogenesis, defense against toxins and parasites, and others. With the exception of the brain and the retina, mature mast cells occupy connective tissues in...

Cell of the Month: Pericytes

It’s a fibroblast-like cell adorned with long cytoplasmic processes that wrap around the endothelial cells in blood vessels, it controls blood flow through the blood vessels, and it is essential for normal brain function and development. Which cell type is it? Well,...

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The Promises and Problems with ADCs

Antibody drug conjugates (ADCs) are targeted cancer therapies that combine the specificity of monoclonal antibodies with the potency of cytotoxic drugs. In contrast to conventional chemotherapies, which do not discriminate between healthy and cancerous cells, ADCs are...

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Tempo offers services and alliances based on our advanced technological platforms and a range of capabilities. Our team differentiates ourselves based on a strong commitment to innovative solutions and quality R&D for our partners.

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On Demand Custom Engineered Cell Models

Tempo develops patient relevant stem cell (iPSCs) based models to support drug discovery, preclinical studies, and early-stage clinical development.