Cell-based models for human diseases

Cell-based assay technology reagents

Chips and Beyond: The Attraction of 3D Organoid Models in Drug Discovery

A critical prerequisite for any drug discovery program is the availability of robust ways to study the disease in question and evaluate how experimental treatments impact disease phenotypes. Disease models ranging from patient-derived cell lines to whole animal models that recapitulate disease phenotypes are indispensable for target identification and validation, proof-of-concept (i.e., for efficacy) experiments and pre-clinical toxicology studies.  The biology of any disease is complex and developing a ‘good’ disease model requires a comprehensive understanding of the underlying disease mechanisms and pathogenesis, both of which are gained by gathering Real-World Evidence and...

iPSC Culture: What Every Researcher Needs to Know

Induced pluripotent stem cells (iPSCs) have become a mainstay in disease modeling and drug development, offering almost unlimited opportunities to study human biology in the lab. However, working with these cells can present hurdles that catch even the most seasoned...

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Cell of the Month – Kupffer Cells

Welcome back to our Cell of the Month series! This time, we are talking about Kupffer cells - what they are, what they do, and why we should want to learn more about them!  Kupffer cells - the gatekeepers of the liver First described by German anatomist Karl Wilhelm...

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The Forgotten Process – Trogocytosis!

Trogocytosis, from trogo meaning ‘to gnaw’ or ‘to nibble’ in Ancient Greek, is an active process during which one cell receives cell surface molecules and membrane fragments from another cell in a unidirectional and cell-contact dependent manner.  Within immune cells,...

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Tempo Bioscience Services

Disease Models and Assay Services

Tempo offers services and alliances based on our advanced technological platforms and a range of capabilities. Our team differentiates ourselves based on a strong commitment to innovative solutions and quality R&D for our partners.

Tempo Bioscience Support

On Demand Custom Engineered Cell Models

Tempo develops patient relevant stem cell (iPSCs) based models to support drug discovery, preclinical studies, and early-stage clinical development.