Cell-based models for human diseases

Cell-based assay technology reagents

2D vs 3D Cell Culture: Choosing the Right Model for Disease Research

In our last article, we compared 2D organ-on-a-chip devices and 3D organoids with respect to their use in drug discovery, highlighting their importance in modeling diseases and evaluating efficacy and safety during drug discovery and development . We also presented the major catch-22 challenge in disease modeling; disease biology is complex and developing a ‘good’ disease model requires a deep understanding of disease mechanisms and pathogenesis, both of which come through gathering Real-World Evidence and modeling the disease. In this article, we take a closer look at some of the most important considerations for choosing an approach to model disease, focusing specifically on 2D...

iPSC Culture: What Every Researcher Needs to Know

Induced pluripotent stem cells (iPSCs) have become a mainstay in disease modeling and drug development, offering almost unlimited opportunities to study human biology in the lab. However, working with these cells can present hurdles that catch even the most seasoned...

read more

Cell of the Month – Kupffer Cells

Welcome back to our Cell of the Month series! This time, we are talking about Kupffer cells - what they are, what they do, and why we should want to learn more about them!  Kupffer cells - the gatekeepers of the liver First described by German anatomist Karl Wilhelm...

read more

The Forgotten Process – Trogocytosis!

Trogocytosis, from trogo meaning ‘to gnaw’ or ‘to nibble’ in Ancient Greek, is an active process during which one cell receives cell surface molecules and membrane fragments from another cell in a unidirectional and cell-contact dependent manner.  Within immune cells,...

read more

Tempo Bioscience Services

Disease Models and Assay Services

Tempo offers services and alliances based on our advanced technological platforms and a range of capabilities. Our team differentiates ourselves based on a strong commitment to innovative solutions and quality R&D for our partners.

Tempo Bioscience Support

On Demand Custom Engineered Cell Models

Tempo develops patient relevant stem cell (iPSCs) based models to support drug discovery, preclinical studies, and early-stage clinical development.