A critical prerequisite for any drug discovery program is the availability of robust ways to study the disease in question and evaluate how experimental treatments impact disease phenotypes. Disease models ranging from patient-derived cell lines to whole animal models that recapitulate disease phenotypes are indispensable for target identification and validation, proof-of-concept (i.e., for efficacy) experiments and pre-clinical toxicology studies.  The biology of any disease is complex and developing a ‘good’ disease model requires a comprehensive understanding of the underlying disease mechanisms and pathogenesis, both of which are gained by gathering Real-World Evidence and...