Models for 10,000 Human Diseases

Tempo-iMG™: Architectural Strategies

Tempo-iMG™ was cited in cell.com in a study that investigated HIV-1 integration in the unexplored microglia reservoir that gives rise to continued HIV replication in infected cells. Scientists used Tempo-iMG™ human iPSC-derived microglia to determine that CTCF, an architectural chromosomal protein, contributes to the viral integration and latency and is found proximally to topologically associated domains (TAD) within H3K36me3-enriched areas. The authors of the article cited Tempo-iMG™ as an accurate, patient-relevant human model that can be used to represent microglial HIV-infections in the human central nervous system. Citation Summary In this citation, researchers investigated...

Tempo-iKidneyPod™: Modeling with Microfluidics

Tempo-iKidneyPod™ was mentioned in springer.com in a review article that summarized various investigative methods and applications of microfluidic chips, specifically to examine how SARS-CoV-2 causes acute kidney injury (AKI). Tempo-iKidneyPod™ is composed of human...

read more

Tempo Bioscience Services

Disease Models and Assay Services

Tempo offers services and alliances based on our advanced technological platforms and a range of capabilities. Our team differentiates ourselves based on a strong commitment to innovative solutions and quality R&D for our partners.

Tempo Bioscience Support

On Demand Custom Engineered Cell Models

Tempo develops patient relevant stem cell (iPSCs) based models to support drug discovery, preclinical studies, and early-stage clinical development.