NASH – The Urgent Need for Better Disease Models and New Therapies

Welcome to our new mini-series about liver organoids. In Part 1, we focus on non-alcoholic steatohepatitis (NASH), a severe and prevalent form of non-alcoholic fatty liver disease for which no drugs have been approved. We look at the current treatment landscape for...
Cell of the Month: Cells in a 3D Spheroid

Cell of the Month: Cells in a 3D Spheroid

Spheroids have been used in cell culture for decades. In the 1980s, different types of human cancer cells --normally grown as monolayers or suspension cultures--were tested for their innate...

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Cell of the Month: Cardiomyocytes

Cell of the Month: Cardiomyocytes

Cardiomyocytes are cardiac muscle cells. They are terminally differentiated and facilitate contractile forces ("beatings") of the heart. Grown in vitro as a monolayer sheath, cardiomyocytes are...

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Cell of the Month: CD34+ Cells

Cell of the Month: CD34+ Cells

Welcome back to our cell of the month series. This time we’re talking about CD34+ cells, a type of undifferentiated multipotent hematopoetic stem cell (HSC) with the potential to differentiate into...

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Cell of the Month: The Kidney

Cell of the Month: The Kidney

Most of us will remember from high school biology class that kidneys comprise part of the excretory system and function in toxin removal, maintaining electrolyte homeostasis and regulating the...

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Cell of the Month: Osteoblasts

Cell of the Month: Osteoblasts

Cell of The Month: Osteoblasts Osteoblasts, often referred to as bone-forming cells, are specialized and terminally differentiated products of mesenchymal stem cells whose major function is to...

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The Many Faces of Phagocytes

The Many Faces of Phagocytes

Most of us were introduced to phagocytosis as a cellular event where dead host cells, microbial cells or their components, or other foreign bodies are engulfed and often destroyed by specialized...

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Disease Models