CRISPR Screen Identifies Potential New Regulators of Fibrosis in Human Liver Cells

In our last few liver articles, we highlighted the urgent need for new models and treatments for non-alcoholic steatohepatitis (NASH), and looked at the potential for human liver organoids to not only model disease, but also to test new drugs for safety and efficacy....
The Many Faces of Phagocytes

The Many Faces of Phagocytes

Most of us were introduced to phagocytosis as a cellular event where dead host cells, microbial cells or their components, or other foreign bodies are engulfed and often destroyed by specialized...

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The Lowdown on Retinal Pigment Epithelium

The Lowdown on Retinal Pigment Epithelium

Have you heard of the retinal pigment epithelium? Well, the retinal pigment epithelium (or RPE) is located at the interface between the light-sensitive outer parts of the visual cells...

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What are motor neurons?

What are motor neurons?

You’re in a bakery full of delicious treats. After a lot of soul-searching, you set your heart on a pecan danish. You reach for your wallet. But wait - how did you go from deciding how wanted your...

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Disease Models