TempoStemBank™

Disease Models and iPSC derivative Cell Types

Applications

TempoStemBank™ are intended for basic scientific research, drug discovery and therapeutics development use only. It is not a product for human testing or diagnostics.


Disease modeling and drug discovery (iPSCs: grown as monolayers vs. colonies)


Developmental and lineage differentiation studies


Scalable for BioBanking (GMP-grade possible


High Content Screening (e.g., expression of differentiation markers)

Disease Models

Frequently Requested Disease Models for iPSC lines or iPS-derived cell types in the ectoderm, endoderm, and mesenchymal lineages:

  • Frontotemporal Dementia (FTD)
  • Familial Alzheimer’s Disease (FAD; early onset; late onset)
  • Parkinson’s Disorder (PD)
  • Multiple Sclerosis (MS)
  • Seizure Disorders (e.g., Epilepsy)
  • Motor Neuron Diseases (e.g., ALS, PLS)
  • Duchenne Muscular Dystrophy (DMD)
  • Spinal Muscular Atrophy (SMA Types I-IV)
  • Friedreich’s Ataxia
  • Cardiomyopathy (e.g., Fabry Disease, Primary arrhythmias)
  • Muscular Dystrophy with Early Contractures and Cardiomyopathy
  • Emery-Dreifuss Muscular Dystrophy (EDMD)
  • Osteogenesis Imperfecta
  • Tourette Syndrome
  • Ataxia-Telangiectasia
  • Huntington Disease
  • Williams Syndrome
  • Spinocerebellar Ataxia
  • Warfan Syndrome
  • Affective Disorders (e.g., Bipolar Disorder, Depression.)
  • Schizophrenia
  • Sensory Neuropathy
  • Diabetes (Types: Familial, Juvenile Onset, or Maturity Onset)
  • Fragile X Syndrome
  • Fabry Disease
  • Angelman’s Syndrome
  • Trisomy 21 (Down Syndrome)
  • Turner Syndrome
  • Sickle Cell Anemia (& carriers)
  • Turcot Syndrome
  • Osteoporosis
  • Paget Disease of Bone
  • Rheumatoid arthritis
  • Bernard-Soulier Syndrome (Giant Platelet Syndrome)
  • Von Hippel-Lindau Syndrome (VHL)
  • Chronic Kidney Diseases
  • Prader-Willi Syndrome (PWS)
  • Charcot-Marie-Tooth Disease
  • Cancer iPSCs (e.g., osteosarcoma, ovarian tumors, colorectal, neuroblastoma, glioblastoma multiforme (GBM), renal cell carcinoma (RCC), head-and-neck)
  • Ethnically Diverse Donors’ Derived iPSCs
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