by Karen O'Hanlon Cohrt | Dec 26, 2023 | Disease Models
It’s a fibroblast-like cell adorned with long cytoplasmic processes that wrap around the endothelial cells in blood vessels, it controls blood flow through the blood vessels, and it is essential for normal brain function and development. Which cell type is it? Well,...
by Karen O'Hanlon Cohrt | Dec 18, 2022 | Trends
Welcome back to our blog series about the blood brain barrier (BBB). In Part 1, we provided a brief history on the discovery of the BBB, and introduced what we currently know about its composition and biological functions. In Part 2, we explain why reliable BBB models...
by Karen O'Hanlon Cohrt | Jan 26, 2023 | Trends
Welcome to Part 3 of our blog series covering the blood brain barrier (BBB). In Part 1, we looked briefly at how the BBB was discovered and presented what we currently know about its composition and functions. Part 2 focused on the need for reliable BBB models in drug...
by Karen O'Hanlon Cohrt | Oct 1, 2018 | Trends
Gene reporter assays have contributed hugely to our understanding of how genes are regulated during growth and development, for example, through the study of spatiotemporal gene expression patterns, as well as how gene expression is regulated by transcription factors,...
by Olwen Reina | Feb 26, 2016 | Cell Culture Techniques
Cancer cell and tissue models are adapted for use in a research setting allowing for the direct study of a complex set of diseases. As models improve, their use in research has proven pivotal to better diagnosing, treating and even preventing cancer. Here, we’ll...
