by Karen O'Hanlon Cohrt | Feb 4, 2025 | Cell Culture Techniques, Disease Models
Induced pluripotent stem cells (iPSCs) have become a mainstay in disease modeling and drug development, offering almost unlimited opportunities to study human biology in the lab. However, working with these cells can present hurdles that catch even the most seasoned...
by Olwen Reina | Feb 26, 2016 | Cell Culture Techniques
Cancer cell and tissue models are adapted for use in a research setting allowing for the direct study of a complex set of diseases. As models improve, their use in research has proven pivotal to better diagnosing, treating and even preventing cancer. Here, we’ll...
by Olwen Reina | Mar 20, 2016 | Cell Culture Techniques
Basement membrane products like Matrigel® and Geltrex™ act as a substrate or physical support for cultured cells helping to create more in vivo-like extracellular matrices. Basement membranes are found ubiquitously in the body. They play a role in a many key cellular...
by Olwen Reina | Jul 3, 2016 | Cell Culture Techniques
There is nothing more tragic than walking into your tissue culture room only to find a researcher curled up on the floor, clasping a flask, and wailing that their cells have been contaminated. It’s a fate I wouldn’t wish on my worst enemy! Hopefully it has...
by Olwen Reina | Jun 3, 2016 | Cell Culture Techniques
Your tissue culture hood, cell culture hood, biosafety cabinet (or BSC), the hood-y thing in your tissue culture room or whatever you like to call it, is a precious tool that requires occasional love. Here we’ll teach you how to correctly clean your hood and...
by Karen O'Hanlon Cohrt | Aug 16, 2018 | Cell Culture Techniques
The remarkable propensity of mesenchymal stem cells (MSCs) for self-renewal, multi-lineage differentiation and immune-modulatory activity has attracted much attention within the cell therapy area, from their potential in cell therapies and research models to their...
