by Karen O'Hanlon Cohrt | Apr 4, 2023 | Disease Models
Welcome to our new mini-series about liver organoids. In Part 1, we focus on non-alcoholic steatohepatitis (NASH), a severe and prevalent form of non-alcoholic fatty liver disease for which no drugs have been approved. We look at the current treatment landscape for...
by Olwen Reina | Mar 4, 2016 | Disease Models
Microglia have been studied extensively for their role in various neurodegenerative diseases and brain injuries, including Alzheimer’s disease, Parkinson’s disease, Epilepsy, Frontal Temporal dementias, Amyotrophic Lateral Sclerosis (ALS), ischemic injury, and...
by Olwen Reina | Apr 4, 2016 | Disease Models
Hepatocytes are widely used to screen potential drug candidates and have allowed researchers to fast-track many new treatments into clinical trials. Quickly releasing new drug treatments that meet the high standards called for by patients and doctors is an immense...
by Olwen Reina | Apr 21, 2016 | Disease Models
A xenograft (or heterograft) is a piece of living tissue taken from a donor of one species and grafted into a recipient of different species. Cancer refers to a group of diseases characterized by uncontrolled division of abnormal cells in a part of the body. According...
by Olwen Reina | May 13, 2016 | Disease Models
Q 1 & 2: What Are Astrocytes? What Do Astrocytes Do? Astrocytes or astroglia are the largest and most numerous types of glial cells (see below) in the Central Nervous System (CNS). There are various subtypes of astrocytes within the different regions of the brain...
by Karen O'Hanlon Cohrt | Feb 22, 2019 | Disease Models
Most of us will remember from high school biology class that kidneys comprise part of the excretory system and function in toxin removal, maintaining electrolyte homeostasis and regulating the body’s acid-base balance. Beyond this, proper kidney function is also...
