by Karen O'Hanlon Cohrt | Dec 9, 2024 | Disease Models
Welcome back to our Cell of the Month series! This time, we are talking about Kupffer cells – what they are, what they do, and why we should want to learn more about them! Kupffer cells – the gatekeepers of the liver First described by German anatomist...
by Karen O'Hanlon Cohrt | Jul 13, 2025 | Cell Culture Techniques, Disease Models
In our last article, we compared 2D organ-on-a-chip devices and 3D organoids with respect to their use in drug discovery, highlighting their importance in modeling diseases and evaluating efficacy and safety during drug discovery and development . We also presented...
by Karen O'Hanlon Cohrt | Apr 9, 2025 | Disease Models
In a previous Cell of The Month article, we explored the biology of the kidney. We highlighted the structure and function of the glomerulus podocytes and proximal tubules; these are specialized cell types found in the nephron, which is the kidney’s key structural and...
by Karen O'Hanlon Cohrt | Apr 4, 2023 | Disease Models
This article was originally published on 4th April 2023. It was revised and republished on 19th March 2023, to reflect important updates in the NASH therapeutic development space, including FDA approval of Rezdiffra in March 2024. Welcome to our new mini-series about...
by Karen O'Hanlon Cohrt | Dec 26, 2023 | Disease Models
It’s a fibroblast-like cell adorned with long cytoplasmic processes that wrap around the endothelial cells in blood vessels, it controls blood flow through the blood vessels, and it is essential for normal brain function and development. Which cell type is it? Well,...
by Olwen Reina | Jul 26, 2016 | Disease Models
Melanocytes are cells that produce melanin, the pigment present in our skin, eyes, and hair. iPS-derived melanocytes are used in models of skin disease, drug toxicity assays, skin bioprinting and in cell therapy R&D. Previously, we looked at the role of melanin...
