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Alzheimer’s Disease – Hypotheses Old and New – Part Two

Alzheimer’s Disease – Hypotheses Old and New – Part Two

by Karen O'Hanlon Cohrt | Nov 27, 2017 | Industry News, Trends

In our last post, we walked through some of the canonical hypotheses surrounding Alzheimer’s Disease (AD), but what about all the other hypotheses that are knocking around? Since AD’s discovery over a century ago countless ideas have emerged, yet the exact cause of...
2D vs 3D Cell Culture: Choosing the Right Model for Disease Research

2D vs 3D Cell Culture: Choosing the Right Model for Disease Research

by Karen O'Hanlon Cohrt | Jul 13, 2025 | Cell Culture Techniques, Disease Models

In our last article, we compared 2D organ-on-a-chip devices and 3D organoids with respect to their use in drug discovery, highlighting their importance in modeling diseases and evaluating efficacy and safety during drug discovery and development . We also presented...
Explore Further: More on Human Podocytes and Proximal Tubules

Explore Further: More on Human Podocytes and Proximal Tubules

by Karen O'Hanlon Cohrt | Apr 9, 2025 | Disease Models

In a previous Cell of The Month article, we explored the biology of the kidney. We highlighted the structure and function of the glomerulus podocytes and proximal tubules; these are specialized cell types found in the nephron, which is the kidney’s key structural and...
Tempo-iOligo™: Major study identifies TMEFF1 as a critical factor for HSV-1 replication in the central nervous system

Tempo-iOligo™: Major study identifies TMEFF1 as a critical factor for HSV-1 replication in the central nervous system

by Karen O'Hanlon Cohrt | Sep 24, 2024 | Citation Alerts

Tempo-iOligo™was cited in Nature in a major infectious disease study that offers the first explanation as to why herpes simplex virus 1 (HSV-1) infection in the brain is very rare, despite the fact that most of us have been infected with the virus. The study used...
Blood Brain Barrier and Inflammatory Cell Types in the Human CNS

Blood Brain Barrier and Inflammatory Cell Types in the Human CNS

by Karen O'Hanlon Cohrt | Jul 24, 2024 | Trends

In our last article, we introduced mast cells, their origins and morphology, and summarized how they are activated during IgE-mediated allergic responses. Here, we shift gears and explore how mast cells, together with microglia and the blood brain barrier, contribute...
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About Tempo BioScience

Fascinated by self-assembly of cells in spheroids or organoids? Excited to develop and characterize functionally relevant human iPSC disease models? Tempo Bioscience is a cash-positive product-focused trendsetter in the areas of human iPSCs and novel proprietary biosensors. We are growing and are looking for key hires to expand.  Join us and be a part of the team that will grow the company from the ground up and build a business that lasts.

Our Mission is to develop patient-relevant iPSC-based models for 10,000+ human diseases to advance science and medicine. 

Our Values are respect, communication, and teamwork.

Resources

Why and How Do We Study Keratinocytes?

Why and How Do We Study Keratinocytes?

In a previous article we introduced keratinocytes and looked at their biological functions and subtypes. Here, we explore some of the main reasons researchers study keratinocytes and the...

read more
2D vs 3D Cell Culture: Choosing the Right Model for Disease Research

2D vs 3D Cell Culture: Choosing the Right Model for Disease Research

In our last article, we compared 2D organ-on-a-chip devices and 3D organoids with respect to their use in drug discovery, highlighting their importance in modeling diseases and evaluating...

read more
Chips and Beyond: The Attraction of 3D Organoid Models in Drug Discovery

Chips and Beyond: The Attraction of 3D Organoid Models in Drug Discovery

A critical prerequisite for any drug discovery program is the availability of robust ways to study the disease in question and evaluate how experimental treatments impact disease phenotypes....

read more
  • Products
    • Biosensor Assays
      • TempoATP™ for ATP Metabolism
      • TempoCAL™ for Calcium
      • TempoMito™ for Mitochondria
      • TempoO2™ for Oxygen Metabolism
      • TempoVOL™ for Cationic Voltage
    • Induced Pluripotent Stem Cells (IPSC)
      • iAstro™ Astrocytes
      • iBMEC™ Brain Microvascular Endothelial Cells
      • iCardio™ Cardiomyocytes
      • iCort™ Cortical Neurons
      • iDopaNer™ Dopaminergic Neurons
      • iHep3D™ Hepatocytes
      • iHepStellate™ Hepatic Stellate
      • iHepStellate™-iKupffer™-iLSEC™-iHep3D™ 3D organoid
      • iKer™ Keratinocytes
      • iKidneyPod™ Kidney Proximal Tubules and Podocyte 3D Spheroids
      • iKupffer™ Kupffer Cells
      • iLSEC™ Liver Sinusoidal Endothelials
      • iMel™ Melanocytes
      • iMG™ Microglia
      • iMono™ CD14+ Monocytes
      • iMotorNer™ Motor Neurons
      • iMSC™ Mesenchymal
      • iNStem™ Neural Progenitor
      • iOligo™ Oligodendrocyte Progenitor
      • iOsteo™ Osteoblasts
      • iPeri™ Pericytes
      • iPhago™ Phagocytes
      • iRPE™ Retinal Pigment Epithelials
      • iSchwann™ Schwann
      • iSenso™ Sensory Neurons
    • TempoStemBank™
    • Cell Culture Solutions
      • Cell Medium Products
      • Assay Reagents
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