by tempo | May 1, 2020 | Disease Models
Vascular endothelium is a thin monolayer of cells that constitute the lining of blood vessels and organs (1-3). A hallmark of many diseases (e.g., cancer, diabetes mellitus, viral infections, etc) is highlighted in the dysfunctional states of the vascular endothelium....
by tempo | Jul 8, 2020 | Cell Culture Techniques
Genetically encoded biosensors have become popular and powerful LIVE-cell reporters in recent years (see reference here). These biosensors can be incorporated into a variety of human inducible pluripotent stem cells (iPSCs) and iPSC-derived cell types (such as...
by Allison Kennedy | Oct 10, 2022 | Citation Alerts
Tempo-iMG™, human iPSC-derived microglia, was used in a follow-up study cited in plos.org. This study expanded on a previous discovery showing that healthy microglia were able to silence HIV. Citation Summary In the current study, scientists from Case Western Reserve...
by Allison Kennedy | Oct 9, 2022 | Citation Alerts
Tempo-iMG™, Tempo-iCort™, Tempo-iDopaNer™, and Tempo-iMotorNer™ were utilized in a study cited in plos.org that examined the cross-talking relationship between microglia and neurons. It was critical that the researchers deployed Tempo’s iPSC-derivative cell types to...