Cell of the Month: Vascular Endothelial Cells

Cell of the Month: Vascular Endothelial Cells

Vascular endothelium is a thin monolayer of cells that constitute the lining of blood vessels and organs (1-3). A hallmark of many diseases (e.g., cancer, diabetes mellitus, viral infections, etc) is highlighted in the dysfunctional states of the vascular endothelium....
Visualizing ATP in a Cell

Visualizing ATP in a Cell

Genetically encoded biosensors have become popular and powerful LIVE-cell reporters in recent years (see reference here). These biosensors can be incorporated into a variety of human inducible pluripotent stem cells (iPSCs) and iPSC-derived cell types (such as...
Tempo-iMG™: Targeting Solutions for HIV

Tempo-iMG™: Targeting Solutions for HIV

Tempo-iMG™, human iPSC-derived microglia, was used in a follow-up study cited in plos.org. This study expanded on a previous discovery showing that healthy microglia were able to silence HIV.  Citation Summary In the current study, scientists from Case Western Reserve...