by tempo | Aug 7, 2019 | Disease Models
Cardiomyocytes are cardiac muscle cells. They are terminally differentiated and facilitate contractile forces (“beatings”) of the heart. Grown in vitro as a monolayer sheath, cardiomyocytes are connected by gap junction proteins that help synchronize...
by Karen O'Hanlon Cohrt | Mar 22, 2019 | Disease Models
Welcome back to our cell of the month series. This time we’re talking about CD34+ cells, a type of undifferentiated multipotent hematopoetic stem cell (HSC) with the potential to differentiate into almost any other blood cell type under specific conditions. As stem...
by Karen O'Hanlon Cohrt | Feb 22, 2019 | Disease Models
Most of us will remember from high school biology class that kidneys comprise part of the excretory system and function in toxin removal, maintaining electrolyte homeostasis and regulating the body’s acid-base balance. Beyond this, proper kidney function is also...
by Karen O'Hanlon Cohrt | Jul 30, 2018 | Disease Models
Cell of The Month: Osteoblasts Osteoblasts, often referred to as bone-forming cells, are specialized and terminally differentiated products of mesenchymal stem cells whose major function is to synthesize bone in a process known as osteogenesis. Osteogenesis During...
by Karen O'Hanlon Cohrt | Mar 4, 2018 | Disease Models
Most of us were introduced to phagocytosis as a cellular event where dead host cells, microbial cells or their components, or other foreign bodies are engulfed and often destroyed by specialized cells known as phagocytes. During my undergraduate studies, phagocytosis...