popular

TempoStemBank™-iPSC: human iPSC lines

Summary

TempoStemBank™-iPSC: human iPSC lines are derived from human dermal/fibroblasts, blood or cord blood, using our proprietary feeder-free, serum-free, virus-free, non-genetic, integration-free under a fully defined proprietary reprogramming conditions. The cells express canonical biomarkers of iPSCs (e.g., Oct4, Tra-1-60, Tra-1-81, Sox2, Nanog, and SSEA-4); they have been proven to be multipotent and are able to differentiate into ectoderm, endoderm and mesoderm derivative cell types. Please inquire for ready-to-ship low passage iPSCs.


Academic scientists receive a special rate! Check out our new citations!

Human iPSC Lines, anti-human-Oct4, ICC

More Views

  • Human iPSC Lines, anti-human-Sox2, ICC

Details

TempoStemBank™-iPSC: human iPSC lines are derived from human dermal/fibroblasts, blood or cord blood, using our proprietary feeder-free, serum-free, virus-free, non-genetic integration-free under a fully defined proprietary reprogramming conditions. The cells express canonical biomarkers of iPSCs (e.g., e.g., Oct4, Tra-1-60, Tra-1-81, Sox2, Nanog, and SSEA-4); they have been proven to be multipotent and are able to differentiate into ectoderm, endoderm and mesoderm derivative cell types.

Please email Tempo Support for Ready-to-Ship low passage iPSCs. Academic scientists receive a special rate!

Frequently Requested Disease Models for iPSC lines or iPS-derived cell types in the ectoderm, endoderm, and mesenchymal lineages:

  • Frontotemporal Dementia (FTD)
  • Familial Alzheimer's Disease (FAD)
  • Parkinson's Disorder (PD)
  • Multiple Sclerosis (MS)
  • Seizure Disorders (e.g., Epilepsy)
  • Motor Neuron Diseases (e.g., ALS, PLS)
  • Duchenne Muscular Dystrophy (DMD)
  • Spinal Muscular Atrophy (SMA Types I-IV)
  • Friedreich's Ataxia
  • Cardiomyopathy (e.g., Fabry's Disease)
  • Ataxia-Telangiectasia
  • Huntington Disease
  • Williams Syndrome
  • Spinocerebellar Ataxia
  • Warfan Syndrome
  • Affective Disorders (e.g., Bipolar Disorder, Depression.)
  • Schizophrenia
  • Fragile X Syndrome
  • Angelman's Syndrome
  • Trisomy 21 (Down Syndrome)
  • Turner Syndrome
  • Sickle Cell Anemia
  • Turcot Syndrome
  • Osteoporosis
  • Rheumatoid arthritis
  • Cancer iPSCs (e.g., osteosarcoma, ovarian tumors, colorectal, neuroblastoma,glioblastoma multiforme (GBM))
  • Ethnically Diverse Donors' Derived iPSCs 
  • Please send inquiry to Tempo Support

Applications:

  • Disease modeling and drug discovery (iPSCs: grown as monolayers vs. colonies)
  • Developmental and lineage differentitation studies
  • High Content Screening (e.g., expression of differentiation markers)
  • Scalable for BioBanking (GMP-grade possible. Please send inquiry to Tempo Support)

Growth Reagents (Suggested):

  • Matrigel hESC-qualified matrix (Corning)
  • 10μM Y-27632 ROCK inhibitor (Sigma)
  • Accutase, for passaging cells (Innovative Cell Technologies)

Custom-Derivation of human iPSC Lines:

Characterizations performed: biomarkers confirmation (e.g., Oct4, Tra-1-60, Tra-1-81, Sox2, Nanog, and SSEA-4), functional assay (upon request)

Approximate turn-around time: ~4-6 weeks (for fibroblast/dermal samples); ~7-9 weeks (for blood samples)

Sample requirements: human dermal cells required: ~5x10^5 cells per donor. For blood or cord blood samples, please contact Tempo Support.

Technology used: an in-house developed proprietary feeder-free, serum-free, viral/genetic-elements-free, integration-free reprogramming method.

Deliverables: >6.0x10^6 cells (Multiple lines or scale-up possible. Please inquire).  BioSafety Level 2.

SKU1002: Please email Tempo Support for ready-to-ship low passage iPSCs. Academic scientists receive a special rate!

We ship worldwide.

Citations:

1) Enhanced Astrocyte Responses are Driven by a Genetic Risk Allele Associated with Multiple Sclerosis

2) The Genetic Multiple Sclerosis (MS) Risk Variant rs7665090-G Increases Astrocyte Responses and Lymphocyte Recruitment to White Matter Lesions.

3) Human Cortex Spheroid with a Functional Blood Brain Barrier for High-Throughput Neurotoxicity Screening and Disease Modeling

 

Additional Information

Product Use TempoStemBank™-iPSC are intended for basic scientific research, drug discovery, and therapeutics development use only. It is not a product for human testing, therapeutics, or diagnostics.