Exosomes

Exosomes

Thirty (30) years ago, exosomes were first described as extracellular vesicles (References 1 and 5). Extracellular vesicles (EVs) are cell derived membrane structures. They are secreted as a result of fusions between intracellular endosomes and the plasma membrane. ...
Visualizing ATP in a Cell

Visualizing ATP in a Cell

Genetically encoded biosensors have become popular and powerful LIVE-cell reporters in recent years (see reference here). These biosensors can be incorporated into a variety of human inducible pluripotent stem cells (iPSCs) and iPSC-derived cell types (such as...
Cell of the Month: Cardiomyocytes

Cell of the Month: Cardiomyocytes

Cardiomyocytes are cardiac muscle cells. They are terminally differentiated and facilitate contractile forces (“beatings”) of the heart. Grown in vitro as a monolayer sheath, cardiomyocytes are connected by gap junction proteins that help synchronize...
Cell of the Month: CD34+ Cells

Cell of the Month: CD34+ Cells

Welcome back to our cell of the month series. This time we’re talking about CD34+ cells, a type of undifferentiated multipotent hematopoetic stem cell (HSC) with the potential to differentiate into almost any other blood cell type under specific conditions. As stem...