Tempo-iCort™: Human iPSC-derived Cortical Neurons

In stock
SKU
201
$885.00

Tempo’s iCort™: human cortical neurons are derived from human dermal cells, using integration-free induced pluripotent stem cell (iPSC) lines under a fully defined proprietary induction and maturation conditions. Tempo’s iCort™ cells are branched structures when plated as a monolayer in culture and express biomarkers such as beta-3-Tuj, GAD65/67, VGLUT1/2, and Map2. iCort™ can be used under maturation conditions, co-culture conditions (with astrocytes), and short-term functional characterization studies. 

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Cortical neurons belong to the family of diverse neurons in the human central nervous system (CNS).   In the CNS, these neurons form networks that are responsible for associative and cognitive functions. There are excitatory projection neurons (PNs) and inhibitory interneurons (INs). They are are implicated in many disabling neurological disorders, including Alzheimer’s and Lofora diseases.

Tempo’s iCort™: human cortical neurons are derived from human dermal cells, using integration-free induced pluripotent stem cell (iPSC) lines under a fully defined proprietary induction and maturation conditions. Tempo’s iCort™ cells are branched structures when plated as a monolayer in culture and express biomarkers such as beta-3-Tuj, GAD65/67, VGLUT1/2, and Map2. iCort™ can be used under maturation conditions, co-culture conditions (with astrocytes), and short-term functional characterization studies.

Applications:

  • Disease modeling
  • Toxicity testing
  • Phenotypic Assays (e.g., expression of differentiation markers)
  • Research and Development of cell therapies in animal models
  • Neuronal differentiation, function, and myelination studies
 
Specifications: ~1.00x10^6 cells per 1ml of freezing medium (vial)
 
Long-term Storage: liquid nitrogen
 
Growth Properties: adherent
 
Technology used: an in-house developed proprietary non-viral, nucleic-acids-free, feeder-free, serum-free, and integration-free reprogramming technology.
 
QC: Sterility, Safety, (BioSafety Level 2), HIV/viruses, bacteria, fungi: negative. Cell viability post-thawing >90%
 
SKU201
 
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Product Use Tempo-iCort™ are intended for scientific research and drug development use only. It is not a product for human testing or diagnostics.