TempoVol™-iCort: Cationic Voltage Biosensor Assay using Human Cortical Neurons
TempoVol™-iCort: cationic voltage biosensor assay using human iPS-derived . They are derived from integration-free induced pluripotent stem cell (iPSC) lines under a fully defined proprietary neural induction and maturation conditions. TempoVol™-iCort cells are polarized structures when plated as a monolayer in culture and express markers such as MAP2 and beta-Tuj. We've validated iCort™ cells to be cationic-conducting neurons when exposed to solutions with fluctuating concentrations of sodium, calcium, potassium, magnesium, and protons/H+. TempoVol™ biosensor is introduced to the cells using proprietary methods and is expressed in the in abundance in the cell.
TempoVol™-iCort: cationic voltage biosensor assay using human iPS-derived . They are derived from integration-free induced pluripotent stem cell (iPSC) lines under a fully defined proprietary neural induction and maturation conditions. TempoVol™-iCort cells are polarized structures when plated as a monolayer in culture and express markers such as MAP2 and beta-Tuj. We've validated iCort™ cells to be cationic-conducting neurons when exposed to solutions with fluctuating concentrations of sodium, calcium, potassium, magnesium, and protons/H+. TempoVol™ biosensor is introduced to the cells using proprietary methods and is expressed in the in abundance in the cell.
Applications:
- Neurotoxicity testing for reporting cellular cationic fluctuations (such as calcium, protons/H+, potassium)
- Phenotypic Assays
- Chemical compound or small molecules screening
- Research and development on animal models for human diseases
- Studying neural maturation, networking and function, and cations-mediated pathways.
Academic scientists receive a special rate!
Specifications: ~1.05x10^6 cells per 1ml of freezing medium (vial)
Long-term Storage: liquid nitrogen
Growth Properties: adherent
Technology used: an in-house developed proprietary feeder-free, serum-free, viral/genetic-elements-free, integration-free reprogramming method.
QC:
Sterility, Safety, (BioSafety Level 2), HIV/viruses, bacteria, fungi: negative
Cell viability post-thawing >90%
SKU202
| Product Use | TempoVol-iCort™ are intended for basic scientific research, drug discovery and therapeutics development use only. It is not a product for human testing or diagnostics. |
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