Biosensors

TempoCal™-iAstro: Tempo’s calcium biosensors are incorporated into induced human astrocytes. They respond to intracellular calcium changes in the 605nm-625nm fluorescent range (Excitation/Emission=610nm/625nm). With excellent signal-to-noise ratios, these biosensors operate on second-to-minute scales.

TempoMito™-iAstro cells contain mitochondrial biosensors in human iPS-derived astrocytes. Disruption of mitochondrial functions in human astrocytes has been implicated in Alzheimer's disorder and ischemia. Tempo's biosensor responds to mitochondrial calcium changes and reports in the 605nm-625nm fluorescent range (Excitation/Emission) as calcium levels increase or decrease. With excellent signal-to-noise ratios, these sensors can operate on second-to-minute scales. This tool provides an efficient way of detecting changes in the mitochondrial organelle and enables high-throughput screening approaches for drug discovery and toxicology screening. 

Academic scientists receive a special rate!

TempoCal^TM calcium biosensors are incorporated into human neural progenitor cells. They respond to intracellular calcium changes in the 605nm-625nm fluorescent range (Excitation/Emission = 610nm/625nm), measuring increases or decreases in cytosolic calcium concentrations. With excellent signal-to-noise ratios, these calcium biosensors can operate on second-to-minute scales. They can be used for single-cell applications, as well as medium to high-throughput screening platforms.

Academic scientists receive a special rate!