Monthly Archives: December 2019

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Written on Dec, 11, 2019 by in

Thirty (30) years ago, exosomes were first described as extracellular vesicles (References 1 and 5). Extracellular vesicles (EVs) are cell derived membrane structures. They are secreted as a result of fusions between intracellular endosomes and the plasma membrane.  Alternatively, they are dispensed from the plasma membrane as microvesicles. Since their initial discovery, exosomes have become implicated in the mechanisms of intercellular signaling (aka. cell-to-cell signaling) and cell-to-cell maintenance of homeostasis. Since their initial discovery, EVs have gained much respect in the cell biology world. They are represented as an important mechanism of cell-to-cell communication — transferring cell membranes, cytosolic proteins, lipids, DNA, RNA, microRNA, etc.  (more…)

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