Monthly Archives: February 2018

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Written on Feb, 20, 2018 by in , ,

Genetic variability can be defined as the genetic differences that exist within or between populations of individuals, and explains the remarkable differences between humans, despite the fact that we share 99.5 % of our DNA with each other.

Genetic variability includes differences in both the coding and non-coding regions of our DNA and is brought about by variants. Simply put, variants are genotype alterations (e.g., mutations) that may or may not result in observable changes (e.g., a novel trait, disease). For any given gene or allele present in a population, a number of variants exist. Variants may be benign e.g., those governing hair and eye color, or pathogenic e.g., the variants associated with some types of cystic fibrosis, diabetes, high blood pressure, and hereditary cardiomyopathy, to name a few.  

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