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The Challenges In Small Molecule Drug Development – Part 3 of our Drug Discoveries Series: To Zs and Z’

The Challenges In Small Molecule Drug Development – Part 3 of our Drug Discoveries Series: To Zs and Z’

by Karen O'Hanlon Cohrt | Jan 16, 2019 | Trends

Welcome back to the drug discovery series! In this post, we journey through target validation and assay development and validation for compound screening! Target Validation As mentioned earlier in the series, most small molecule drugs function by modulating the...

About Tempo BioScience

Fascinated by self-assembly of cells in spheroids or organoids? Excited to develop and characterize functionally relevant human iPSC disease models? Tempo Bioscience is a cash-positive product-focused trendsetter in the areas of human iPSCs and novel proprietary biosensors. We are growing and are looking for key hires to expand.  Join us and be a part of the team that will grow the company from the ground up and build a business that lasts.

Our Mission is to develop patient-relevant iPSC-based models for 10,000+ human diseases to advance science and medicine. 

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Resources

Tempo-iMG™: Architectural Strategies

Tempo-iMG™: Architectural Strategies

Tempo-iMG™ was cited in cell.com in a study that investigated HIV-1 integration in the unexplored microglia reservoir that gives rise to continued HIV replication in infected cells. Scientists...

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NASH – The Urgent Need for Better Disease Models and New Therapies

NASH – The Urgent Need for Better Disease Models and New Therapies

Welcome to our new mini-series about liver organoids. In Part 1, we focus on non-alcoholic steatohepatitis (NASH), a severe and prevalent form of non-alcoholic fatty liver disease for which no...

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Better Blood Brain Barrier Models Are Urgently Needed for Modern Therapeutic Advances

Better Blood Brain Barrier Models Are Urgently Needed for Modern Therapeutic Advances

Welcome to Part 4 of our series about the blood brain barrier (BBB)! Here, we highlight the rising global burden of neurological disorders, and recap on the challenges surrounding drug safety...

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      • TempoATP™ for ATP Metabolism
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      • TempoVOL™ for Cationic Voltage
    • Induced Pluripotent Stem Cells (IPSC)
      • iAstro™ Astrocytes
      • iBMEC™ Brain Microvascular Endothelial Cells
      • iCardio™ Cardiomyocytes
      • iCort™ Cortical Neurons
      • iDopaNer™ Dopaminergic Neurons
      • iHep3D Hepatocytes
      • iHepStellate Hepatic Stellate
      • iHepStellate™-iKupffer™-iLSEC™-iHep3D™ 3D organoid
      • iKer™ Keratinocytes
      • iKidneyPod™ Kidney Proximal Tubules and Podocyte 3D Spheroids
      • iKupffer Kupffer Cells
      • iLSEC Liver Sinusoidal Endothelials
      • iMel™ Melanocytes
      • iMG™ Microglia
      • iMono™ CD14+ Monocytes
      • iMotorNer™ Motor Neurons
      • iMSC™ Mesenchymal
      • iNStem™ Neural Progenitor
      • iOligo™ Oligodendrocyte Progenitor
      • iOsteo™ Osteoblasts
      • iPeri™ Pericytes
      • iPhago™ Phagocytes
      • iRPE™ Retinal Pigment Epithelials
      • iSchwann™ Schwann
      • iSenso™ Sensory Neurons
    • TempoStemBank™
    • Cell Culture Solutions
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