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Alzheimer’s Disease – Hypotheses Old and New – Part Two

Alzheimer’s Disease – Hypotheses Old and New – Part Two

by Karen O'Hanlon Cohrt | Nov 27, 2017 | Trends

In our last post, we walked through some of the canonical hypotheses surrounding Alzheimer’s Disease (AD), but what about all the other hypotheses that are knocking around? Since AD’s discovery over a century ago countless ideas have emerged, yet the exact cause of...
Alzheimer’s Disease – Hypotheses Old and New – Part One

Alzheimer’s Disease – Hypotheses Old and New – Part One

by Karen O'Hanlon Cohrt | Nov 7, 2017 | Trends

The Discovery of Alzheimer’s Disease The Alzheimer’s story began when the German physician Dr. Aloysius Alzheimer reported distinctive plaques and neurofibrillary tangles in the brains of deceased individuals in a series of case study reports, published in the early...

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Sources of cells for modeling the human BBB — 4 considerations

Sources of cells for modeling the human BBB — 4 considerations

Welcome to Part 3 of our blog series covering the blood brain barrier (BBB). In Part 1, we looked briefly at how the BBB was discovered and presented what we currently know about its...

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In Vitro Blood Brain Barrier Models for Drug Development

In Vitro Blood Brain Barrier Models for Drug Development

Welcome back to our blog series about the blood brain barrier (BBB). In Part 1, we provided a brief history on the discovery of the BBB, and introduced what we currently know about its...

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Tempo-iMG™ and Tempo-iOligo™: Two New Puzzle Pieces

Tempo-iMG™ and Tempo-iOligo™: Two New Puzzle Pieces

Tempo-iMG™ and Tempo-iOligo™ were cited by scientists in a nature.com study where they built a 3D in vitro organoid model of the blood brain barrier (BBB). They chose to build their BBB model...

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  • Products
    • Biosensor Assays
      • TempoATP™ for ATP Metabolism
      • TempoCAL™ for Calcium
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    • Induced Pluripotent Stem Cells (IPSC)
      • iAstro™ Astrocytes
      • iBMEC™ Brain Microvascular Endothelial Cells
      • iCardio™ Cardiomyocytes
      • iCort™ Cortical Neurons
      • iDopaNer™ Dopaminergic Neurons
      • iHep™ Hepatocytes
      • iKer™ Keratinocytes
      • iKidneyPod™ Kidney Proximal Tubules and Podocyte 3D Spheroids
      • iMel™ Melanocytes
      • iMG™ Microglia
      • iMono™ CD14+ Monocytes
      • iMotorNer™ Motor Neurons
      • iMSC™ Mesenchymal
      • iNStem™ Neural Progenitor
      • iOligo™ Oligodendrocyte Progenitor
      • iOsteo™ Osteoblasts
      • iPeri™ Pericytes
      • iPhago™ Phagocytes
      • iRPE™ Retinal Pigment Epithelials
      • iSchwann™ Schwann
      • iSenso™ Sensory Neurons
    • TempoStemBank™
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