Custom Microglia

Summary

Tempo-iMG™: Human iPS-derived Microglia (Custom Product)
Tempo’s iMG™ cells are reprogrammed from human iPS-derived multipotent progenitor cells, using integration-free induced pluripotent stem cell (iPSC) lines under a fully defined proprietary serum-free, virus-free, genetic-elements-free, and integration-free conditions. Tempo’s iMG™ cells are polarized structures when plated as a monolayer in culture and express microglia biomarkers, CXCR3 and CD11b/c. Please inquire for ready-to-ship Human iPS-derived iMicroglia.

Custom Microglia;  anti-CXCR3 antibody staining

More Views

  • Custom Microglia; anti-CD11b/c antibody staining
  • Custom Microglia; Tempo-iMG cells calcium responses

Details

Tempo-iMG™: Human iPS-derived Microglia (Custom Product)
Tempo’s iMG™ cells are reprogrammed from human iPS-derived multipotent progenitor cells, using integration-free induced pluripotent stem cell (iPSC) lines under a fully defined proprietary serum-free, virus-free, genetic-elements-free, and integration-free conditions. Tempo’s iMG™ cells are polarized structures when plated as a monolayer in culture and express microglia biomarkers, CXCR3 and CD11b/c. Please inquire for ready-to-ship Human iPS-derived iMicroglia.

Applications:

  • Disease modeling
  • Toxicity testing
  • Phenotypic Screening (e.g., cytokine secretion, expression of differentiation markers)
  • In vitro assays using microglial cells

Academic scientists receive a special rate!

Custom-Derivation of human iPS-derived Microglia:

Characterizations performed: biomarkers confirmation (CXCR3 and CD11b/c); calcium imaging; inflammation assays;

Approximate turn-around time: ~3-5 weeks (from iPSCs colonies)

Sample requirements: human fibroblasts or iPSCs, ~5x10^5 cells. Please contact us, if you'd prefer to use blood samples

Technology used: an in-house developed proprietary feeder-free, serum-free, viral/genetic-elements-free, integration-free reprogramming method.

Deliverables: >2x10^6 cells (scale-up possible). BioSafety Level 2.

SKU1001

Additional Information

Product Use Custom Microglia are intended for basic scientific research drug discovery, and therapeutics development use only. It is not a product for human testing or diagnostics.